SCHEMBL22149253

SCHEMBL22149253

CCCC(N)c1cc(O)cc(=O)o1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
CYP3A4 P08684 3/20 0.44
GLA P06280 2/20 0.44
HSD17B3 P37058 4/20 0.39
ALDH1A1 P00352 8/20 0.37
GAA P10253 3/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPK1 P28482 2/20 0.37
ERAP1 Q9NZ08 1/20 0.37
MAPKAPK2 P49137 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
NQO1 P15559 1/20 0.35
HPGD P15428 3/20 0.34
CASP7 P55210 3/20 0.34
HSD17B10 Q99714 3/20 0.34
LMNA P02545 2/20 0.34
CYP2C9 P11712 2/20 0.34
TSHR P16473 2/20 0.34
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22149723 1.00 MEN1 (0.44) MEN1KMT2ACYP3A4GLAHSD17B3
SCHEMBL22149504 0.81 CA1 (0.44) KMT2AGLAALDH1A1GAAKDM4E
SCHEMBL22149740 0.81 CA1 (0.44) KMT2AGLAALDH1A1GAAKDM4E
SCHEMBL22149727 0.80 CYP3A4 (0.38) MEN1KMT2ACYP3A4GLAHSD17B3
SCHEMBL25964843 0.79 CYP3A4 (0.44) MEN1KMT2ACYP3A4GLAHSD17B3
SCHEMBL22149728 0.79 CYP3A4 (0.44) MEN1KMT2ACYP3A4GLAHSD17B3
SCHEMBL22149509 0.77 MAPT (0.44) MEN1KMT2ACYP3A4GLAALDH1A1
SCHEMBL22149256 0.77 MAPT (0.44) MEN1KMT2ACYP3A4GLAALDH1A1
SCHEMBL22149518 0.77 MAPT (0.44) MEN1KMT2ACYP3A4GLAALDH1A1
SCHEMBL24264467 0.76 ALDH1A1 (0.42) MEN1KMT2ACYP3A4GLAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020127194-A1 ANTICANCER COMPOUNDS PHARMA MAR, S.A. (ES) 2020-06-25 WO disclosed