Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 18/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150196 | 0.99 | HDAC8 (0.39) | HDAC8HDAC3NCOR2HDAC2HDAC1 | |
| SCHEMBL22149955 | 0.96 | SMN1; SMN2 (0.38) | HDAC8HDAC3NCOR2HDAC2HDAC1 | |
| SCHEMBL22149742 | 0.83 | HDAC3 (0.42) | HDAC8HDAC3NCOR2HDAC2HDAC1 | |
| SCHEMBL22122705 | 0.83 | SMN1; SMN2 (0.41) | HDAC8HDAC3NCOR2HDAC2HDAC1 | |
| SCHEMBL22150190 | 0.82 | SMN1; SMN2 (0.41) | HDAC8HDAC3NCOR2HDAC2HDAC1 | |
| SCHEMBL22149741 | 0.82 | EGFR (0.38) | HDAC8HDAC3NCOR2 | |
| SCHEMBL23810206 | 0.80 | KDM4E (0.41) | HDAC8HDAC3HDAC2HDAC1HDAC6 | |
| SCHEMBL22122715 | 0.80 | SMN1; SMN2 (0.43) | HDAC8HDAC3NCOR2HDAC2HDAC1 | |
| SCHEMBL23810139 | 0.79 | SMN1; SMN2 (0.42) | HDAC8HDAC3HDAC2HDAC1HDAC4 | |
| SCHEMBL22150881 | 0.77 | GAA (0.37) | HDAC8HDAC3NCOR2HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018103-B2 | Flow cell and methods | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-06-25 | — | — | US | disclosed |
| US-20220372182-A1 | FLOW CELL AND METHODS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-11-24 | — | — | US | disclosed |
| US-20220185927-A1 | HYDROGEL | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-16 | — | — | US | disclosed |
| US-20210284609-A1 | HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-09-16 | — | — | US | disclosed |
| WO-2021110700-A1 | HYDROGEL | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-10 | — | — | WO | disclosed |
| WO-2020126598-A1 | HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284609-A1 | HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS | POLL, PCNA, DNMT3A | HDAC8 1617/4885HDAC3 3176/4885NCOR2 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.