SCHEMBL22149741

SCHEMBL22149741

C=CC(=O)NCCOCCOCC(=O)Nc1ccc(CN=[N+]=[N-])nc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ EGFR P00533 4/20 0.38
▸ KDM4E B2RXH2 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ CRBN Q96SW2 2/20 0.33
▸ CA12 O43570 2/20 0.32
▸ CA1 P00915 2/20 0.32
▸ CA2 P00918 2/20 0.32
▸ CA4 P22748 2/20 0.32
▸ CA9 Q16790 2/20 0.32
▸ CA14 Q9ULX7 2/20 0.32
▸ HDAC8 Q9BY41 2/20 0.32
▸ HDAC3 O15379 1/20 0.32
▸ NCOR2 Q9Y618 1/20 0.32
▸ ITK Q08881 4/20 0.31
▸ APP P05067 1/20 0.31
▸ HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22149737 0.84 CA12 (0.38) EGFRKDM4EMEN1MAPTKMT2A
SCHEMBL22149955 0.83 SMN1; SMN2 (0.38) EGFRKDM4EMEN1MAPTKMT2A
SCHEMBL22150196 0.82 HDAC8 (0.39) HDAC8HDAC3NCOR2
SCHEMBL22149736 0.82 HDAC8 (0.40) HDAC8HDAC3NCOR2
SCHEMBL23810206 0.72 KDM4E (0.41) KDM4EHDAC8HDAC3
SCHEMBL17060912 0.71 P4HTM (0.37) KDM4EMEN1MAPTKMT2AHDAC8
SCHEMBL17060910 0.71 P4HTM (0.37) KDM4EMEN1MAPTKMT2AHDAC8
SCHEMBL22150193 0.71 GAA (0.39) KDM4EMEN1MAPTKMT2ACA12
SCHEMBL22122705 0.70 SMN1; SMN2 (0.41) KDM4EMEN1MAPTKMT2AHDAC8
SCHEMBL22122701 0.70 CYP1A1 (0.46) KDM4EMEN1MAPTKMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018103-B2 Flow cell and methods ILLUMINA CAMBRIDGE LIMITED (GB) 2024-06-25 — — US disclosed
US-20220372182-A1 FLOW CELL AND METHODS ILLUMINA CAMBRIDGE LIMITED (GB) 2022-11-24 — — US disclosed
US-20220185927-A1 HYDROGEL ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-16 — — US disclosed
US-20210284609-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2021-09-16 — — US disclosed
WO-2021110700-A1 HYDROGEL ILLUMINA CAMBRIDGE LIMITED (GB) 2021-06-10 — — WO disclosed
WO-2020126598-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2020-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210284609-A1 HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS POLL, PCNA, DNMT3A EGFR 1973/4885KDM4E 3663/4885MEN1 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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