Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150873 | 0.95 | GAA (0.41) | GAASMN1; SMN2LMNACA12CA1 | |
| SCHEMBL22150193 | 0.83 | GAA (0.39) | GAASMN1; SMN2LMNACA12CA1 | |
| SCHEMBL22150881 | 0.79 | GAA (0.37) | GAASMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL23476624 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL29403601 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL22501648 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL23810139 | 0.73 | SMN1; SMN2 (0.42) | GAASMN1; SMN2CA1CA2MAPT | |
| SCHEMBL22150190 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL22149742 | 0.71 | HDAC3 (0.42) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22149953 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284609-A1 | HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-09-16 | — | — | US | disclosed |
| WO-2020126598-A1 | HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210284609-A1 | HETEROCYCLIC AZIDE UNITS AND THEIR USE IN POLYMER COATINGS | POLL, PCNA, DNMT3A | GAA 1031/4885SMN1; SMN2 1789/4885LMNA 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.