Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149742 | 0.84 | HDAC3 (0.42) | SMN1; SMN2HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22150190 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22149953 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL23810139 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22150873 | 0.78 | GAA (0.41) | SMN1; SMN2HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22150194 | 0.75 | GAA (0.43) | SMN1; SMN2HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL3731214 | 0.75 | HDAC1 (0.74) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2619354 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL22501648 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL29403601 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110700-A1 | HYDROGEL | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-10 | — | — | WO | disclosed |