Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.52 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684418 | 1.00 | STING1 (0.52) | STING1TBK1OPRK1 | |
| SCHEMBL28751728 | 1.00 | STING1 (0.52) | STING1TBK1OPRK1 | |
| SCHEMBL29685013 | 0.87 | STING1 (0.49) | STING1TBK1 | |
| SCHEMBL22150267 | 0.87 | STING1 (0.49) | STING1TBK1 | |
| SCHEMBL28751744 | 0.87 | STING1 (0.49) | STING1TBK1 | |
| SCHEMBL22150418 | 0.86 | STING1 (0.50) | STING1TBK1 | |
| SCHEMBL22150302 | 0.86 | STING1 (0.63) | STING1TBK1 | |
| SCHEMBL19451659 | 0.85 | STING1 (0.71) | STING1TBK1 | |
| SCHEMBL28597016 | 0.85 | STING1 (0.71) | STING1TBK1 | |
| SCHEMBL22151336 | 0.85 | STING1 (0.48) | STING1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585623-A | Bis [ N- ((5-carbamoyl) -1H-benzo [ d ] imidazol-2-yl) pyrazole-5-carboxamide ] derivatives and related compounds as STING (interferon gene stimulator) agonists for the treatment of cancer | 梅尔莎纳医疗公司 | 2022-06-03 | — | — | CN | claimed |
| CN-114585623-A | Bis [ N- ((5-carbamoyl) -1H-benzo [ d ] imidazol-2-yl) pyrazole-5-carboxamide ] derivatives and related compounds as STING (interferon gene stimulator) agonists for the treatment of cancer | 梅尔莎纳医疗公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |