Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 11/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28599228 | 0.99 | STING1 (0.49) | STING1KDM4EGAAPKMUSP2 | |
| SCHEMBL30182113 | 0.83 | STING1 (0.49) | STING1KDM4EGAAPKMUSP2 | |
| SCHEMBL20075498 | 0.80 | STING1 (0.56) | STING1KDM4EUSP2TDP1 | |
| SCHEMBL23234059 | 0.80 | HTR1A (0.44) | STING1KDM4EGAAPKMUSP2 | |
| SCHEMBL28522082 | 0.78 | STING1 (0.56) | STING1KDM4EGAAPKMUSP2 | |
| SCHEMBL30412798 | 0.77 | STING1 (0.65) | STING1 | |
| SCHEMBL22135066 | 0.77 | STING1 (0.57) | STING1USP2 | |
| SCHEMBL19436532 | 0.77 | STING1 (0.68) | STING1 | |
| SCHEMBL29776116 | 0.77 | STING1 (0.43) | STING1KDM4EGAAPKMUSP2 | |
| Bromide SCHEMBL23327843 | 0.76 | STING1 (0.67) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |