Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121339 | 0.94 | KDM4E (0.53) | IDO1TDO2PTGER4GPR119KDM4E | |
| SCHEMBL22150045 | 0.90 | GPR119 (0.46) | IDO1TDO2GPR119KDM4EPKM | |
| SCHEMBL22121217 | 0.87 | GPR119 (0.51) | GPR119KDM4EPKMCHEK2 | |
| SCHEMBL21511698 | 0.85 | PTGER4 (0.51) | IDO1TDO2PTGER4KDM4ECHEK2 | |
| SCHEMBL21496879 | 0.85 | PTGER4 (0.51) | IDO1TDO2PTGER4KDM4ECHEK2 | |
| SCHEMBL29848332 | 0.83 | IDO1 (0.51) | IDO1TDO2PTGER4GPR119KDM4E | |
| SCHEMBL2429883 | 0.82 | IDO1 (0.51) | IDO1TDO2GPR119KDM4EPKM | |
| SCHEMBL13834763 | 0.81 | IDO1 (0.55) | IDO1TDO2GPR119KDM4EPKM | |
| SCHEMBL22716710 | 0.81 | KDM4E (0.52) | IDO1TDO2PTGER4GPR119KDM4E | |
| SCHEMBL22121263 | 0.80 | KMT2A (0.53) | GPR119KDM4EPKMCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |