Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 16/20 | 0.43 |
| ▸ | JAK1 | P23458 | 16/20 | 0.43 |
| ▸ | TYK2 | P29597 | 16/20 | 0.43 |
| ▸ | JAK3 | P52333 | 16/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121411 | 0.89 | KMT2A (0.52) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL22151391 | 0.86 | KMT2A (0.49) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL22121416 | 0.82 | KMT2A (0.57) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL22151399 | 0.79 | STING1 (0.46) | KMT2ASTING1 | |
| SCHEMBL28602277 | 0.79 | KMT2A (0.46) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL28602275 | 0.79 | KMT2A (0.46) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL22151677 | 0.77 | STING1 (0.56) | STING1 | |
| SCHEMBL22151665 | 0.76 | KDM4E (0.55) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL19436567 | 0.75 | KMT2A (0.50) | KMT2AJAK2JAK1TYK2JAK3 | |
| SCHEMBL19436528 | 0.75 | KMT2A (0.50) | KMT2AJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |