SCHEMBL221518

SCHEMBL221518

O=C(O)c1ccccc1C(F)(F)F

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.62
GAA P10253 1/20 0.62
ALDH1A1 P00352 4/20 0.56
ALOX15 P16050 1/20 0.56
TAS2R14 Q9NYV8 3/20 0.56
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
FABP4 P15090 1/20 0.54
MAPT P10636 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
GRIK1 P39086 1/20 0.50
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
CTNNB1 P35222 1/20 0.50
WNT3A P56704 1/20 0.50
HPGD P15428 2/20 0.49
CNR2 P34972 1/20 0.49
KDM4E B2RXH2 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30449216 1.00 LMNA (0.62) LMNAGAAALDH1A1ALOX15TAS2R14
SCHEMBL27815762 0.98 LMNA (0.60) LMNAGAAALDH1A1ALOX15TAS2R14
SCHEMBL27794599 0.98 LMNA (0.60) LMNAGAAALDH1A1ALOX15TAS2R14
SCHEMBL27815764 0.98 LMNA (0.60) LMNAGAAALDH1A1ALOX15TAS2R14
SCHEMBL9461001 0.98 LMNA (0.60) LMNAGAAALDH1A1ALOX15TAS2R14
Hydrochloric Acid SCHEMBL2533965 0.98 LMNA (0.60) LMNAGAAALDH1A1ALOX15TAS2R14
SCHEMBL29208535 0.98 LMNA (0.60) LMNAGAAALDH1A1ALOX15TAS2R14
Ammonia Solution, Strong SCHEMBL27794593 0.98 LMNA (0.60) LMNAGAAALDH1A1ALOX15TAS2R14
Ethylene SCHEMBL714453 0.96 LMNA (0.58) LMNAGAAALDH1A1ALOX15TAS2R14
Formic Acid SCHEMBL27990904 0.92 LMNA (0.55) LMNAGAAALDH1A1ALOX15TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2740 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011411-A Preparation method and application of o-trifluoromethyl benzoic acid modified Ni-Mg-MOF-74 北京化工大学 2026-05-12 CN claimed
US-20260079397-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING CURED PRODUCT TORAY INDUSTRIES, INC. (JP) 2026-03-19 US claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4597224-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING CURED PRODUCT Toray Industries, Inc. (JP) 2025-08-06 EP claimed
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120004715-A Synthesis method of 2-trifluoromethyl benzoic acid 天津均凯农业科技有限公司 2025-05-16 CN claimed
CN-119907612-A Perovskite precursor solution, perovskite solar cell and preparation method of perovskite precursor solution 中国科学技术大学 2025-04-29 CN claimed
CN-119895333-A Photosensitive composition, cured product, electronic component, and method for producing cured product 东丽株式会社 2025-04-25 CN claimed
CN-119777031-A Polysaccharide-based thermoplastic composite fiber and preparation method thereof 中国科学院化学研究所 2025-04-08 CN claimed
US-5422277-A Compound for preserving intracellular morphology, compound for fixing internal components of cell, compound which facilitates transport of components across cell membranes, compound for increasing permeability of membranes ORTHO DIAGNOSTIC SYSTEMS INC. (US) 1995-06-06 US claimed
EP-0562877-A2 Cell fixative and method of staining cells without destroying the cell surface ORTHO DIAGNOSTIC SYSTEMS INC. (a New Jersey corp.) (US) 1993-09-29 EP claimed
US-5219477-A Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid THE DOW CHEMICAL COMPANY (US) 1993-06-15 US claimed
US-5185471-A Reacting 5-halo-2-nitrobenzotrifluorides with inorganic base to form 1,1*-oxy-Bis(3-trifluoromethyl-4-nitrobenzen using benzoate catalyst OCCIDENTAL CHEMICAL CORPORATION (US) 1993-02-09 US claimed
US-4968852-A PHOSPHINE-RHODIUM COMPLEX DECARBONYLATION CATALYST CENTRAL GLASS COMPANY, LIMITED (JP) 1990-11-06 US claimed
US-4929753-A Preparation of trifluoromethylbenzoic acid from hexafluoroxylene CENTRAL GLASS COMPANY, LIMITED (JP) 1990-05-29 US claimed
EP-0302525-A2 Quinolones as antibacterial agents WARNER-LAMBERT COMPANY (US) 1989-02-08 EP claimed
US-4780319-A DRUG DELIVERY USING POLYORTHOESTERS COATINGS MERCK & CO., INC. (US) 1988-10-25 US claimed
EP-0118661-B1 FLUORINE-CONTAINING BENZOPHENONE DERIVATIVES Daikin Kogyo Co., Ltd. (JP) 1988-04-13 EP claimed
EP-0118661-A2 Fluorine-containing benzophenone derivatives Daikin Kogyo Co., Ltd. (JP) 1984-09-19 EP claimed