Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69983 | 0.81 | TDP1 (0.51) | TDP1PTGS1PTGS2TRPV1HTT | |
| SCHEMBL19703433 | 0.80 | MAPT (0.46) | MAPTTP53GAAHTT | |
| SCHEMBL15625462 | 0.78 | TDP1 (0.38) | TDP1PTGS1PTGS2TRPV1SCN9A | |
| SCHEMBL21725670 | 0.78 | TDP1 (0.38) | TDP1PTGS1PTGS2MAPTTP53 | |
| SCHEMBL13035770 | 0.76 | PTGER3 (0.42) | TDP1PTGS1PTGS2SMN1; SMN2AOC3 | |
| SCHEMBL24486502 | 0.74 | PDE3B (0.51) | TDP1TP53SMN1; SMN2HTT | |
| SCHEMBL18737439 | 0.74 | NOTUM (0.60) | TDP1MAPTTP53 | |
| SCHEMBL13085655 | 0.74 | AR (0.42) | TDP1 | |
| SCHEMBL13085614 | 0.72 | NPY5R (0.39) | TDP1 | |
| SCHEMBL10224285 | 0.71 | REN (0.44) | TDP1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104865-A1 | ANTI-EGFR ANTIBODY DRUG CONJUGATES | AbbVie Inc. (US) | 2022-12-21 | — | — | EP | disclosed |
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | disclosed |