Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 17/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.41 |
| ▸ | LCK | P06239 | 7/20 | 0.41 |
| ▸ | TTK | P33981 | 2/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177730 | 1.00 | PTK6 (0.49) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL30177849 | 0.95 | PTK6 (0.51) | PTK6AURKBLCKTTK | |
| SCHEMBL22123960 | 0.95 | PTK6 (0.51) | PTK6AURKBLCKTTK | |
| SCHEMBL22153194 | 0.92 | PTK6 (0.53) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL30177795 | 0.92 | PTK6 (0.53) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL30178017 | 0.89 | PTK6 (0.50) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL22124998 | 0.89 | PTK6 (0.50) | PTK6AURKBLCKTTKMAPKAPK5 | |
| SCHEMBL30183757 | 0.89 | PTK6 (0.61) | PTK6AURKBLCKTTK | |
| SCHEMBL22123379 | 0.89 | PTK6 (0.61) | PTK6AURKBLCKTTK | |
| SCHEMBL22124192 | 0.88 | PTK6 (0.48) | PTK6AURKBLCKTTKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |