Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 19/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 8/20 | 0.41 |
| ▸ | LCK | P06239 | 8/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25173549 | 0.93 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25167695 | 0.93 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25173592 | 0.92 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25176078 | 0.92 | PTK6 (0.42) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL22124387 | 0.92 | PTK6 (0.41) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25170424 | 0.91 | PTK6 (0.41) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL22124270 | 0.90 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL30386118 | 0.90 | PTK6 (0.38) | PTK6JAK2JAK1 | |
| SCHEMBL25170405 | 0.90 | PTK6 (0.38) | PTK6JAK2JAK1 | |
| SCHEMBL30386112 | 0.90 | PTK6 (0.38) | PTK6JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |