Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 15/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.34 |
| ▸ | LCK | P06239 | 6/20 | 0.34 |
| ▸ | JAK2 | O60674 | 4/20 | 0.32 |
| ▸ | JAK1 | P23458 | 4/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30177638 | 0.97 | PTK6 (0.38) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25170322 | 0.93 | PTK6 (0.37) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL22153365 | 0.90 | PTK6 (0.48) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25173592 | 0.90 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL32675710 | 0.90 | PTK6 (0.39) | PTK6AURKBLCKTBK1 | |
| SCHEMBL24112644 | 0.90 | PTK6 (0.39) | PTK6AURKBLCKTBK1 | |
| SCHEMBL30385560 | 0.90 | PTK6 (0.35) | PTK6JAK2JAK1TBK1 | |
| SCHEMBL24112641 | 0.90 | PTK6 (0.39) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25167695 | 0.90 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL25173549 | 0.90 | PTK6 (0.40) | PTK6AURKBLCKJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897839-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |