Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 6/20 | 0.43 |
| ▸ | TTK | P33981 | 14/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124372 | 0.92 | PTK6 (0.46) | PTK6TTKLCKAURKB | |
| SCHEMBL24112317 | 0.85 | PTK6 (0.47) | PTK6TTKLCKAURKB | |
| SCHEMBL22124582 | 0.85 | PTK6 (0.47) | PTK6TTKLCKAURKB | |
| Hydrochloric Acid SCHEMBL30172098 | 0.84 | PTK6 (0.46) | PTK6TTKLCKAURKB | |
| SCHEMBL22124293 | 0.83 | PTK6 (0.46) | PTK6TTKLCKAURKB | |
| SCHEMBL22124124 | 0.83 | TTK (0.49) | PTK6TTKLCKAURKB | |
| SCHEMBL22123995 | 0.83 | PTK6 (0.48) | PTK6TTKLCKAURKB | |
| Hydrochloric Acid SCHEMBL25170356 | 0.83 | PTK6 (0.45) | PTK6TTKLCKAURKB | |
| SCHEMBL22124987 | 0.82 | PTK6 (0.48) | PTK6TTKLCKAURKB | |
| SCHEMBL25450713 | 0.82 | PTK6 (0.45) | PTK6TTKLCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |