Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22154816 | 1.00 | ANPEP (0.41) | ANPEPENPEPMMEGRB2PPARA | |
| SCHEMBL27124358 | 0.87 | SLC7A5 (0.53) | ANPEPENPEPMMESLC7A5 | |
| SCHEMBL24140474 | 0.87 | SLC7A5 (0.53) | ANPEPENPEPMMESLC7A5 | |
| SCHEMBL25818343 | 0.87 | ENPEP (0.41) | ANPEPENPEPMMEGRB2MMP2 | |
| SCHEMBL25831733 | 0.87 | ENPEP (0.41) | ANPEPENPEPMMEGRB2MMP2 | |
| SCHEMBL17728727 | 0.87 | EPHX1 (0.53) | ANPEPMMEMMP2SLC7A5EPHX1 | |
| SCHEMBL17728729 | 0.87 | EPHX1 (0.53) | ANPEPMMEMMP2SLC7A5EPHX1 | |
| SCHEMBL28208789 | 0.87 | EPHX1 (0.53) | ANPEPMMEMMP2SLC7A5EPHX1 | |
| SCHEMBL22121182 | 0.86 | MME (0.44) | ANPEPENPEPMMEGRB2HPGD | |
| SCHEMBL22154239 | 0.86 | MME (0.44) | ANPEPENPEPMMEGRB2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132658-A2 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |