Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2D3 | P61077 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.32 |
| ▸ | TAS2R46 | P59540 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20642938 | 1.00 | UBE2D3 (0.79) | UBE2D3MAPTL3MBTL1CD274TAS2R46 | |
| SCHEMBL20642945 | 0.94 | UBE2D3 (0.85) | UBE2D3CD274TAS2R46MEN1RECQL | |
| SCHEMBL20642950 | 0.89 | UBE2D3 (0.78) | UBE2D3MEN1KMT2A | |
| SCHEMBL20642972 | 0.89 | UBE2D3 (0.78) | UBE2D3MEN1KMT2A | |
| SCHEMBL20642994 | 0.88 | UBE2D3 (1.00) | UBE2D3MAPTBRD4 | |
| SCHEMBL20642947 | 0.88 | UBE2D3 (0.79) | UBE2D3MAPTMEN1KMT2ATDP1 | |
| SCHEMBL22155109 | 0.88 | UBE2D3 (0.79) | UBE2D3MAPTMEN1KMT2ATDP1 | |
| SCHEMBL20642952 | 0.88 | UBE2D3 (0.79) | UBE2D3 | |
| SCHEMBL20642993 | 0.88 | UBE2D3 (0.79) | UBE2D3MAPTMEN1KMT2ATDP1 | |
| SCHEMBL21951134 | 0.88 | UBE2D3 (1.00) | UBE2D3MAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034663-B2 | Tetrahydronaphtho[1,2-b]furan-2(3H)-one derivatives and preparation and uses thereof | Shanghai Qingdong Biotechnology Co., Ltd (CN) | 2021-06-15 | — | — | US | disclosed |
| US-20200199089-A1 | TETRAHYDRONAPHTHO[1,2-B]FURAN-2(3H)-ONE DERIVATIVES AND PREPARATION AND USES THEREOF | Shanghai Qingdong Biotechnology Co., Ltd. (CN) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199089-A1 | TETRAHYDRONAPHTHO[1,2-B]FURAN-2(3H)-ONE DERIVATIVES AND PREPARATION AND USES THEREOF | NR0B1, FOXM1, CYP1A1 | UBE2D3 2113/4885MAPT 4541/4885L3MBTL1 3137/4885 |
| US-11034663-B2 | Tetrahydronaphtho[1,2-b]furan-2(3H)-one derivatives and preparation and uses thereof | NR0B1, FOXM1, CYP1A1 | UBE2D3 2113/4885MAPT 4541/4885L3MBTL1 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.