Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 4/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.30 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | BRD2 | P25440 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22155386 | 0.96 | KDM4E (0.39) | KMT2AKDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL440035 | 0.90 | KDM4E (0.45) | KMT2AKDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL437624 | 0.89 | KDM4E (0.46) | KMT2AKDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL440755 | 0.86 | KDM4E (0.41) | KMT2AKDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL438619 | 0.85 | KDM4E (0.41) | KMT2AKDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL22155388 | 0.84 | ALOX5 (0.35) | ALOX5ALDH1A1MAPK1 | |
| SCHEMBL437648 | 0.84 | PRKDC (0.40) | KMT2AKDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL371292 | 0.84 | ALOX5 (0.51) | KMT2AKDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL438618 | 0.84 | ALOX5 (0.51) | KMT2AKDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL29572728 | 0.84 | ALOX5 (0.51) | KMT2AKDM4ESMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220109116-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-04-07 | — | — | US | disclosed |
| WO-2020127176-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220109116-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, EPHA6, ERCC1 | KMT2A 1528/4885KDM4E 2653/4885SMN1; SMN2 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.