SCHEMBL22157178

SCHEMBL22157178

N#Cc1c(-n2c3ccccc3c3cc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)ccc32)ccc(-c2c(F)c(F)c(F)c(F)c2F)c1-n1c2ccccc2c2cc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)ccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 1/20 0.33
ADORA2A P29274 3/20 0.32
ADORA1 P30542 3/20 0.32
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PDE9A O76083 1/20 0.31
PDE1C Q14123 1/20 0.31
HSD17B10 Q99714 2/20 0.31
ALDH1A1 P00352 2/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22158542 0.97 ADORA1 (0.33) SQORADORA2AADORA1KDM4ESMN1; SMN2
SCHEMBL22157245 0.94 SQOR (0.33) SQORADORA2AADORA1KDM4ESMN1; SMN2
SCHEMBL22157288 0.91 SQOR (0.32) SQORADORA2AADORA1KDM4ESMN1; SMN2
SCHEMBL22157179 0.91 ADORA1 (0.33) SQORADORA2AADORA1KDM4ESMN1; SMN2
SCHEMBL22156589 0.91 PDE9A (0.33) SQORADORA2AADORA1PDE9APDE1C
SCHEMBL22158543 0.89 SQOR (0.31) SQORSMN1; SMN2CLK4
SCHEMBL22157429 0.89 SQOR (0.36) SQORADORA2AADORA1KDM4ESMN1; SMN2
SCHEMBL22157128 0.89 SQOR (0.35) SQORADORA2AADORA1KDM4ESMN1; SMN2
SCHEMBL22156546 0.88 ADORA1 (0.33) SQORADORA2AADORA1KDM4ESMN1; SMN2
SCHEMBL22157239 0.88 ADORA2A (0.32) SQORADORA2AADORA1SMN1; SMN2PDE9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200203628-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200203628-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, OR51E2 SQOR 302/4885ADORA2A 4520/4885ADORA1 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.