Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 13/20 | 0.47 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123392 | 0.89 | TTK (0.51) | TTKPTK6FYNCFTRKDM1A | |
| SCHEMBL30171705 | 0.89 | TTK (0.51) | TTKPTK6FYNCFTRKDM1A | |
| SCHEMBL22122904 | 0.88 | FYN (0.52) | TTKFYN | |
| SCHEMBL30172068 | 0.88 | FYN (0.52) | TTKFYN | |
| SCHEMBL22122845 | 0.88 | TTK (0.50) | TTKPTK6CFTRKDM1AHDAC1 | |
| SCHEMBL30171597 | 0.88 | TTK (0.50) | TTKPTK6CFTRKDM1AHDAC1 | |
| SCHEMBL22124603 | 0.88 | TTK (0.50) | TTKPTK6CFTRKDM1AHDAC1 | |
| SCHEMBL22154474 | 0.87 | TTK (0.50) | TTKPTK6KDM1AHDAC1 | |
| SCHEMBL22122908 | 0.84 | TTK (0.52) | TTKPTK6 | |
| SCHEMBL30172072 | 0.84 | TTK (0.52) | TTKPTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| WO-2020126953-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |