Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.32 |
| ▸ | PNLIP | P16233 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172017 | 0.93 | PTK6 (0.40) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL30171981 | 0.93 | PTK6 (0.40) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL22122996 | 0.93 | PTK6 (0.40) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL30171949 | 0.93 | PTK6 (0.40) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL22123050 | 0.93 | PTK6 (0.40) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL22124640 | 0.93 | PTK6 (0.40) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL22122941 | 0.93 | PTK6 (0.41) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL30171741 | 0.93 | PTK6 (0.41) | PTK6KDM4EGAASMN1; SMN2LCK | |
| SCHEMBL24112493 | 0.91 | PTK6 (0.41) | PTK6LCKAURKBEGFRERBB2 | |
| SCHEMBL25450748 | 0.90 | PTK6 (0.39) | PTK6LCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126953-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |