Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | TTK | P33981 | 3/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.34 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123603 | 0.92 | KDM4E (0.38) | KDM4EGAASMN1; SMN2KDRTTK | |
| SCHEMBL30171778 | 0.85 | TTK (0.39) | KDM4EGAASMN1; SMN2KDRTTK | |
| SCHEMBL22123763 | 0.85 | TTK (0.39) | KDM4EGAASMN1; SMN2KDRTTK | |
| SCHEMBL24910483 | 0.82 | KDM4E (0.43) | KDM4EGAASMN1; SMN2TTKHTR2A | |
| SCHEMBL30171553 | 0.82 | PTK6 (0.43) | KDM4EGAASMN1; SMN2TTKPTK6 | |
| SCHEMBL22122922 | 0.82 | PTK6 (0.43) | KDM4EGAASMN1; SMN2TTKPTK6 | |
| SCHEMBL25444479 | 0.80 | PTK6 (0.42) | KDM4EGAASMN1; SMN2TTKPTK6 | |
| SCHEMBL22123141 | 0.79 | TTK (0.38) | KDRTTKPTK6MAPKAPK5HTR2A | |
| SCHEMBL22139111 | 0.79 | PTK6 (0.39) | KDRTTKPTK6MAPKAPK5 | |
| SCHEMBL30171947 | 0.79 | PTK6 (0.39) | KDRTTKPTK6MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126953-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |