SCHEMBL2216548

SCHEMBL2216548

CC(C)(C)c1ccc(OP(=O)(O)Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1.[LiH]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CYP2C19 P33261 1/20 0.38
TRPV1 Q8NER1 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 2/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276516 0.98 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL29373261 0.98 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL27659647 0.97 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL28227981 0.97 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
Ammonia Solution, Strong SCHEMBL28310052 0.97 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
Hydroquinone SCHEMBL29717355 0.92 LMNA (0.44) APEX1CA1CA2CA9CYP2C19
SCHEMBL28181138 0.91 APEX1 (0.37) APEX1CA1CA2CA9CYP2C19
SCHEMBL21541942 0.90 INPPL1 (0.44) APEX1CA1CA2CA9CYP2C19
SCHEMBL27910299 0.90 INPPL1 (0.44) APEX1CA1CA2CA9CYP2C19
SCHEMBL22077222 0.90 TRPV1 (0.38) APEX1CA1CA2CA9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2749599-B1 USE OF A POLYLACTIC ACID RESIN MOLDED ARTICLE FOR RESIN PARTS FOR AUTOMOBILES ADEKA CORP (JP) 2016-09-21 EP disclosed
EP-2749598-B1 USE OF A POLYLACTIC ACID RESIN MOLDED ARTICLE FOR RESIN PARTS FOR ELECTRICAL APPLICATIONS ADEKA CORP (JP) 2016-08-24 EP disclosed
US-9133121-B2 Weakly basic hindered amines compounds having carbonate skeletons, synthetic resin compositions and coating compositions NEGISHI YOSHINORI (JP) 2015-09-15 US disclosed
EP-2253667-B1 USE OF A POLYLACTIC ACID RESIN MOLDED ARTICLE FOR BUILDING MATERIALS ADEKA CORP (JP) 2015-03-25 EP disclosed
EP-2749598-A1 Use of a polylactic acid resin molded article for resin parts for electrical applications Adeka Corporation (JP) 2014-07-02 EP disclosed
EP-2749599-A1 Use of a polylactic acid resin molded article for resin parts for automobiles Adeka Corporation (JP) 2014-07-02 EP disclosed
US-20130023611-A1 Weakly Basic Hindered Amines Compounds Having Carbonate Skeletons, Synthetic Resin Compositions And Coating Compositions ADEKA CORPORATION (JP) 2013-01-24 US disclosed
US-8329787-B2 Weakly basic hindered amines compounds having carbonate skeletons, synthetic resin compositions and coating compositions ADEKA CORPORATION (JP) 2012-12-11 US disclosed
EP-1731508-B1 WEAKLY BASIC HINDERED AMINES HAVING CARBONATE SKELETONS, SYNTHETIC RESIN COMPOSITIONS, AND COATING COMPOSITIONS ADEKA CORP (JP) 2012-08-01 EP disclosed
EP-1889871-B1 RESIN COMPOSITION CONTAINING ALUMINUM PIGMENT ADEKA CORP (JP) 2011-07-27 EP disclosed
EP-2253667-A1 POLYLACTIC ACID RESIN COMPOSITION Adeka Corporation (JP) 2010-11-24 EP disclosed
US-20100190898-A1 Weakly Basic Hindered Amines Compounds Having Carbonate Skeletons, Synthetic Resin Compositions And Coating Compositions NEGISHI YOSHINORI 2010-07-29 US disclosed
US-20090111699-A1 Weakly Basic Hindered Amines Having Carbonate Skeletons, Synthetic Resin Compositions, And Coating Compositions ADEKA CORPORATION (JP) 2009-04-30 US disclosed
EP-1889871-A1 RESIN COMPOSITION CONTAINING ALUMINUM PIGMENT Adeka Corporation (JP) 2008-02-20 EP disclosed
EP-1731508-A1 WEAKLY BASIC HINDERED AMINES HAVING CARBONATE SKELETONS, SYNTHETIC RESIN COMPOSITIONS, AND COATING COMPOSITIONS Adeka Corporation (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023611-A1 Weakly Basic Hindered Amines Compounds Having Carbonate Skeletons, Synthetic Resin Compositions And Coating Compositions H1-2, H1-4, H1-3 APEX1 2663/4885CA1 852/4885CA2 544/4885
US-20090111699-A1 Weakly Basic Hindered Amines Having Carbonate Skeletons, Synthetic Resin Compositions, And Coating Compositions H1-2, H1-3, H1-4 APEX1 2490/4885CA1 786/4885CA2 398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.