Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 2/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GALK1 | P51570 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL22118274 | 0.88 | MAPT (0.40) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL33439 | 0.88 | HTT (0.42) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL21358774 | 0.86 | MAPT (0.43) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL149876 | 0.86 | MAPT (0.46) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL11350903 | 0.84 | HTT (0.42) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL5606305 | 0.84 | HTT (0.42) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL7117809 | 0.84 | MAPT (0.44) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL8303 | 0.84 | DNMT1 (0.48) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL4612122 | 0.83 | DNMT1 (0.41) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL6387848 | 0.83 | MAPT (0.41) | MAPTHTTTP53STAT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072629-B2 | Reprogramming of cellular adhesion | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-27 | — | — | US | disclosed |
| US-20170305955-A1 | Reprogramming of Cellular Adhesion | UNITED STATES GOVERNMENT | 2017-10-26 | — | — | US | disclosed |
| US-9650407-B2 | Reprogramming of cellular adhesion | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-16 | — | — | US | disclosed |
| US-20140294782-A1 | Reprogramming of Cellular Adhesion | US ARMY, SECRETARY OF THE ARMY | 2014-10-02 | — | — | US | disclosed |
| EP-2773327-A1 | REPROGRAMMING OF CELLULAR ADHESION | The Regents of The University of California (US) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013067203-A1 | REPROGRAMMING OF CELLULAR ADHESION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-10 | — | — | WO | disclosed |
| US-20110177156-A1 | Sterol-Modified Amphiphilic Lipids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-07-21 | — | — | US | disclosed |
| EP-2219587-A1 | STEROL-MODIFIED AMPHIPHILIC LIPIDS | The Regents of the University of California (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009064696-A1 | STEROL-MODIFIED AMPHIPHILIC LIPIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177156-A1 | Sterol-Modified Amphiphilic Lipids | SREBF1, SREBF2, SGMS1 | MAPT 2307/4885HTT 2662/4885TP53 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.