Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | CDK4 | P11802 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692047 | 0.91 | MAPT (0.64) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL9911550 | 0.84 | MAPT (0.64) | MAPTALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL29611317 | 0.84 | MAPT (0.66) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL1250315 | 0.84 | MAPT (0.66) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL3651216 | 0.82 | ALDH1A1 (0.72) | MAPTALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL14892696 | 0.82 | MAPT (0.62) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL8241650 | 0.82 | ALDH1A1 (0.85) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| Indolylpropionic Acid SCHEMBL29374161 | 0.82 | MAPT (0.68) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL28378507 | 0.82 | MAPT (0.68) | MAPTALDH1A1GAAKMT2AMEN1 | |
| Indolylpropionic Acid SCHEMBL195405 | 0.82 | MAPT (0.68) | MAPTALDH1A1KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | UNIV YALE (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230121337-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. | 2023-04-20 | — | — | US | disclosed |
| WO-2020135569-A1 | ETHYLENEDIAMINE COMPOUND AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230121337-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CDK2, CDK20, CDK2AP2 | MAPT 3481/4885ALDH1A1 3716/4885KDM4E 2512/4885 |
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | ASGR1, LDLR, FCGR2A | MAPT 4775/4885ALDH1A1 3256/4885KDM4E 4040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.