Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532349 | 1.00 | ITGB1 (0.33) | ITGB1ITGA4ITGB7F2PYGL | |
| SCHEMBL21878967 | 0.95 | F2 (0.33) | F2PYGL | |
| SCHEMBL20026745 | 0.95 | F2 (0.33) | F2PYGL | |
| SCHEMBL21878969 | 0.95 | F2 (0.33) | F2PYGL | |
| SCHEMBL17492915 | 0.95 | F2 (0.33) | F2PYGL | |
| SCHEMBL17492914 | 0.95 | F2 (0.33) | F2PYGL | |
| SCHEMBL17539195 | 0.91 | F2 (0.32) | F2PYGL | |
| SCHEMBL17532348 | 0.91 | F2 (0.32) | ITGB1ITGA4ITGB7F2PYGL | |
| SCHEMBL17532353 | 0.91 | F2 (0.32) | F2PYGL | |
| SCHEMBL17492937 | 0.91 | F2 (0.34) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |