SCHEMBL21878967

SCHEMBL21878967

CCC1CCC([C@H]2CC=C(c3cnc(-c4ccc(C[C@H](NC(=O)c5ccc(C(C)(C)C)s5)C(=O)N5CC(C(=O)O)C5)cc4)nc3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 4/20 0.33
▸ PYGL P06737 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20026745 1.00 F2 (0.33) F2PYGL
SCHEMBL21878969 1.00 F2 (0.33) F2PYGL
SCHEMBL17492914 1.00 F2 (0.33) F2PYGL
SCHEMBL17492915 1.00 F2 (0.33) F2PYGL
SCHEMBL17492937 0.96 F2 (0.34) F2
SCHEMBL17492938 0.96 F2 (0.34) F2
SCHEMBL22167188 0.95 F2 (0.31) F2PYGL
SCHEMBL17492907 0.95 F2 (0.31) F2PYGL
SCHEMBL17459563 0.95 F2 (0.31) F2PYGL
SCHEMBL22167410 0.95 ITGB1 (0.33) F2PYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3519407-B1 DIMETHYLAMINOETHANOL SALT OF A GLP-1 RECEPTOR MODULATOR RECEPTOS LLC (US) 2021-09-22 — — EP disclosed
US-11066395-B2 Dimethylaminoethanol salt of a GLP-1 receptor modulator RECEPTOS LLC (US) 2021-07-20 — — US disclosed
US-20200131164-A1 DIMETHYLAMINOETHANOL SALT OF A GLP-1 RECEPTOR MODULATOR RECEPTOS LLC 2020-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131164-A1 DIMETHYLAMINOETHANOL SALT OF A GLP-1 RECEPTOR MODULATOR GLP1R, GIPR, GPR119 F2 4749/4885PYGL 1787/4885
US-11066395-B2 Dimethylaminoethanol salt of a GLP-1 receptor modulator GLP1R, GIPR, GPR119 F2 4749/4885PYGL 1787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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