Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21503655 | 0.86 | KMT2A (0.55) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL320568 | 0.83 | KMT2A (0.51) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL1948876 | 0.81 | KMT2A (0.67) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL13596197 | 0.80 | KMT2A (0.56) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL2713283 | 0.80 | KMT2A (0.56) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL29177198 | 0.79 | HDAC1 (0.50) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL2608928 | 0.79 | KDM4E (0.58) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL15457043 | 0.79 | KMT2A (0.47) | KMT2AKDM4EMEN1CYP1A2CYP2C9 | |
| SCHEMBL12332368 | 0.78 | LMNA (0.54) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL14254840 | 0.78 | NPSR1 (0.63) | KMT2AKDM4EMEN1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3889154-A1 | HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020135771-A1 | HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2020-07-02 | — | — | WO | disclosed |