Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23877994 | 1.00 | USP2 (0.50) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL31040994 | 0.89 | USP2 (0.50) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL1655537 | 0.89 | USP2 (0.50) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL10172553 | 0.88 | USP2 (0.53) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL9974295 | 0.88 | USP2 (0.53) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL10172566 | 0.88 | USP2 (0.53) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL19448345 | 0.87 | USP2 (0.49) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL18689612 | 0.87 | USP2 (0.49) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL19439155 | 0.87 | USP2 (0.49) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL1919855 | 0.87 | USP2 (0.49) | USP2SMN1; SMN2RECQLEPHA2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020135771-A1 | HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2020-07-02 | — | — | WO | disclosed |