Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22169569 | 1.00 | PRCP (0.36) | PRCPCTNNB1KDM4EGAAHSD17B10 | |
| SCHEMBL19631726 | 1.00 | PRCP (0.36) | PRCPCTNNB1KDM4EGAAHSD17B10 | |
| SCHEMBL19631882 | 1.00 | PRCP (0.36) | PRCPCTNNB1KDM4EGAAHSD17B10 | |
| SCHEMBL19631737 | 1.00 | PRCP (0.36) | PRCPCTNNB1KDM4EGAAHSD17B10 | |
| SCHEMBL19631825 | 1.00 | PRCP (0.36) | PRCPCTNNB1KDM4EGAAHSD17B10 | |
| SCHEMBL21221669 | 0.88 | OPRM1 (0.38) | PRCPHTR1ADRD2 | |
| SCHEMBL21221812 | 0.88 | OPRM1 (0.38) | PRCPHTR1ADRD2 | |
| SCHEMBL19631808 | 0.88 | OPRM1 (0.38) | PRCPHTR1ADRD2 | |
| SCHEMBL22169600 | 0.88 | OPRM1 (0.38) | PRCPHTR1ADRD2 | |
| SCHEMBL19631760 | 0.88 | OPRM1 (0.38) | PRCPHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458450-B1 | TETRAHYDROPYRAN DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2020-07-01 | — | — | EP | disclosed |