Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 11/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221697 | 1.00 | CYP2C9 (0.57) | CYP2C9ALDH1A1MAPTLMNARARB | |
| Hydrochloric Acid SCHEMBL10971557 | 0.99 | CYP2C9 (0.56) | CYP2C9ALDH1A1MAPTLMNARARB | |
| Hydrochloric Acid SCHEMBL10971561 | 0.99 | CYP2C9 (0.56) | CYP2C9ALDH1A1MAPTLMNARARB | |
| SCHEMBL26364932 | 0.96 | CYP2C9 (0.53) | CYP2C9ALDH1A1MAPTLMNARARB | |
| SCHEMBL17173620 | 0.96 | CYP2C9 (0.58) | CYP2C9ALDH1A1MAPTLMNARARB | |
| SCHEMBL220859 | 0.96 | CYP2C9 (0.61) | CYP2C9ALDH1A1MAPTLMNARARB | |
| SCHEMBL220860 | 0.96 | CYP2C9 (0.61) | CYP2C9ALDH1A1MAPTLMNARARB | |
| SCHEMBL2492365 | 0.94 | CYP2C9 (0.59) | CYP2C9ALDH1A1MAPTLMNARARB | |
| SCHEMBL9352218 | 0.94 | CYP2C9 (0.59) | CYP2C9ALDH1A1MAPTLMNARARB | |
| Hydrochloric Acid SCHEMBL8556826 | 0.94 | CYP2C9 (0.59) | CYP2C9ALDH1A1MAPTLMNARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234402-B2 | Mesogen compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2025-02-25 | — | — | US | disclosed |
| US-20230383187-A1 | Mesogen Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2023-11-30 | — | — | US | disclosed |
| US-11773326-B2 | Mesogen compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2023-10-03 | — | — | US | disclosed |
| EP-3894514-B1 | MESOGEN COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2022-11-23 | — | — | EP | disclosed |
| US-20220049161-A1 | Mesogen Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2022-02-17 | — | — | US | disclosed |
| EP-3894514-A1 | MESOGEN COMPOUNDS | Transitions Optical, Ltd. (IE) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020120282-A1 | MESOGEN COMPOUNDS | TRANSITIONS OPTICAL, LTD. (IE) | 2020-06-18 | — | — | WO | disclosed |
| EP-3045971-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-2652553-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-04-06 | — | — | EP | disclosed |
| EP-2652553-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| US-5328643-A | Electrooptic display, switches, modulators; physical and chemical stability and spontaneous polarization | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0351782-A2 | Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition | HITACHI, LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |
| EP-0341713-A2 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |
| US-4708441-A | LIQUID CRYSTALS | HOFFMAN-LA ROCHE INC. (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0144648-B1 | LIQUID CRYSTALS: DERIVATIVES OF CYCLOHEXYLBENZENE AND CYCLOHEXYLBIPHENYL | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-10-21 | — | — | EP | disclosed |
| US-4652089-A | PACKING FOR CHROMATOGRAPHY COLUMNS, ELECTRO-OPTICAL CELLS | HOFFMANN-LA ROCHE INC. (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0103681-B1 | TETRA- AND PENTACYCLIC MONOESTERS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-07-30 | — | — | EP | disclosed |
| US-4550981-A | Liquid crystalline esters and mixtures | HOFFMANN-LA ROCHE INC. (US) | 1985-11-05 | — | — | US | disclosed |
| US-4526704-A | Esters containing phenylene and cyclohexylene rings | HOFFMANN-LA ROCHE INC. (US) | 1985-07-02 | — | — | US | disclosed |
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |