SCHEMBL2492365

SCHEMBL2492365

CCCCCCC1CCC(c2ccc(C(=O)O)cc2)CC1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.59
ALDH1A1 P00352 2/20 0.57
MAPT P10636 2/20 0.57
LMNA P02545 1/20 0.57
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPK1 P28482 1/20 0.50
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
RARB P10826 8/20 0.46
PLA2G4B P0C869 1/20 0.46
RARA P10276 1/20 0.46
MTOR P42345 1/20 0.46
SPHK1 Q9NYA1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2976660 1.00 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL2976664 1.00 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL9352218 1.00 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL220859 0.99 CYP2C9 (0.61) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL220860 0.99 CYP2C9 (0.61) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL10832130 0.97 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1
Hydrochloric Acid SCHEMBL8556829 0.97 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL10832120 0.97 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1
Hydrochloric Acid SCHEMBL8556826 0.97 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL10832126 0.97 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104927879-B Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal display element JSR株式会社 2018-09-18 CN disclosed
US-9976085-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
CN-105969404-B Liquid crystal aligning agent, liquid crystal alignment film formed by liquid crystal aligning agent and liquid crystal display element 奇美实业股份有限公司 2018-03-23 CN disclosed
CN-105969404-A Liquid crystal aligning agent, liquid crystal alignment film formed by liquid crystal aligning agent and liquid crystal display element 奇美实业股份有限公司 2016-09-28 CN disclosed
CN-105567257-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element CHI MEI CORP 2016-05-11 CN disclosed
US-20160122652-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2016-05-05 US disclosed
CN-103571502-B Crystal aligning agent and compound JSR CO., LTD. (JP) 2016-05-04 CN disclosed
CN-103374353-B The manufacture method of crystal aligning agent, liquid crystal orienting film, liquid crystal display device and liquid crystal display device JSR CO., LTD. (JP) 2016-01-20 CN disclosed
US-20150337013-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS MERCK SHARP & DOHME CORP. (US) 2015-11-26 US disclosed
CN-103131431-B MATERIALS FOR DISPLAY, crystal aligning agent and liquid crystal display device JSR CO., LTD. (JP) 2015-10-07 CN disclosed
EP-2379580-B1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CUBIST PHARM INC (US) 2013-10-23 EP disclosed
CN-103320146-A Liquid crystal aligning agent, liquid crystal aligning film, liquid crystal display element and method of making liquid crystal display element JSR CORP 2013-09-25 CN disclosed
US-8507647-B2 Antibacterial agents for the treatment of gram positive infections CUBIST PHARMACEUTICALS, INC. (US) 2013-08-13 US disclosed
CN-103131431-A Display material, liquid crystal alignment agent and liquid crystal display element JSR CORP 2013-06-05 CN disclosed
CN-102311739-A The method of manufacture of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CORP 2012-01-11 CN disclosed
CN-102236209-A Producing method of liquid crystal display element, polymer composition and liquid crystal display element JSR CORP 2011-11-09 CN disclosed
EP-2379580-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS Cubist Pharmaceuticals, Inc. (US) 2011-10-26 EP disclosed
CN-102053425-A Liquid crystal display element manufacturing method , polymer composition and liquid crystal display element JSR CORP 2011-05-11 CN disclosed
US-20100184649-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CUBIST PHARMACEUTICALS, INC. 2010-07-22 US disclosed
WO-2010075215-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CUBIST PHARMACEUTICALS, INC. (US) 2010-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150337013-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CLPP, CLPTM1, RPN1 CYP2C9 4640/4885ALDH1A1 4703/4885MAPT 4574/4885
US-20100184649-A1 NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS CLPP, CLPTM1, RPN1 CYP2C9 4640/4885ALDH1A1 4703/4885MAPT 4574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.