SCHEMBL22169604

SCHEMBL22169604

CC1(C)CC(C#N)(N2CCCC2)CCO1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.79
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18458519 0.79 ALDH1A1 (0.63) ALDH1A1
SCHEMBL18458523 0.77 ALDH1A1 (0.60) ALDH1A1
SCHEMBL19631876 0.74 ALDH1A1 (0.56) ALDH1A1
SCHEMBL18458522 0.74 ALDH1A1 (0.56) ALDH1A1
SCHEMBL19631958 0.73 ALDH1A1 (0.54) ALDH1A1TSHR
SCHEMBL1349548 0.70 ALDH1A1 (0.37) ALDH1A1
SCHEMBL733892 0.69 ALDH1A1 (0.40) ALDH1A1
SCHEMBL26341304 0.69 ALDH1A1 (0.44) ALDH1A1
SCHEMBL21221680 0.68 ALDH1A1 (0.49) ALDH1A1TSHR
SCHEMBL3237003 0.68 ALDH1A1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458450-B1 TETRAHYDROPYRAN DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN ESTEVE PHARMACEUTICALS SA (ES) 2020-07-01 EP disclosed