SCHEMBL22170451

SCHEMBL22170451

BCCc1ccc(OC2CNC2)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 8/20 0.45
HTR2C P28335 5/20 0.45
HTR2B P41595 5/20 0.45
HTR6 P50406 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22170436 0.81 SLC6A4 (0.41) SLC6A4HTR2CHTR2BHTR6
SCHEMBL22170641 0.80 KCNH2 (0.39) SLC6A4HTR6
SCHEMBL327249 0.79 KCNH2 (0.47) SLC6A4HTR2CHTR2B
SCHEMBL327185 0.76 CRHBP (0.49) SLC6A4
SCHEMBL23286032 0.76 KCNH2 (0.36) SLC6A4
SCHEMBL22170688 0.76 KCNH2 (0.35) SLC6A4
SCHEMBL22170495 0.75 SLC6A4 (0.37) SLC6A4HTR2CHTR2B
SCHEMBL1394218 0.74 CRHBP (0.47) SLC6A4
SCHEMBL14578228 0.73 HTR2C (0.50) HTR2CHTR2B
SCHEMBL22170611 0.73 KCNH2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020138499-A1 ALKYL-SUBSTITUTED COMPOUND 大日本住友製薬株式会社 2020-07-02 WO disclosed