Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22172319 | 0.84 | ALDH1A1 (0.54) | DPP4ALDH1A1KDM4EPOLBVEGFA | |
| SCHEMBL24507281 | 0.82 | IDO1 (0.49) | DPP4ALDH1A1KDM4EVEGFAEGLN1 | |
| SCHEMBL30560055 | 0.82 | IDO1 (0.49) | DPP4ALDH1A1KDM4EVEGFAEGLN1 | |
| SCHEMBL28424017 | 0.82 | IDO1 (0.49) | DPP4ALDH1A1KDM4EVEGFAEGLN1 | |
| SCHEMBL2843836 | 0.81 | ALDH1A1 (0.69) | DPP4ALDH1A1KDM4EPOLBVEGFA | |
| SCHEMBL1872135 | 0.81 | DPP4 (0.58) | DPP4KDM4EGPR119 | |
| SCHEMBL17109170 | 0.81 | ALDH1A1 (0.58) | DPP4ALDH1A1KDM4EPOLBVEGFA | |
| SCHEMBL23434788 | 0.81 | VEGFA (0.53) | DPP4ALDH1A1KDM4EPOLBVEGFA | |
| SCHEMBL6128555 | 0.80 | SMARCA2 (0.51) | DPP4ALDH1A1KDM4EPOLBGPR119 | |
| SCHEMBL20971874 | 0.80 | VEGFA (0.57) | ALDH1A1KDM4EPOLBVEGFAEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020135507-A1 | POLYSUBSTITUTED ANILINOPYRIMIDINE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | 杭州百新生物医药科技有限公司 | 2020-07-02 | — | — | WO | disclosed |