Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421713 | 0.92 | PIK3CD (0.45) | KDM4EPIK3CDPOLBSIGMAR1 | |
| SCHEMBL27381771 | 0.85 | PIK3CD (0.38) | KDM4EALDH1A1ALOX15PIK3CDPOLB | |
| SCHEMBL23732159 | 0.84 | PIK3CD (0.42) | ALDH1A1PIK3CDPOLBSIGMAR1 | |
| SCHEMBL21164490 | 0.84 | POLB (0.45) | PIK3CDPOLBSIGMAR1 | |
| SCHEMBL17308232 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1ALOX15POLBMEN1 | |
| SCHEMBL25046201 | 0.83 | OPRL1 (0.40) | PIK3CD | |
| SCHEMBL3262537 | 0.83 | PIK3CD (0.39) | PIK3CDPOLB | |
| SCHEMBL24267755 | 0.83 | OPRL1 (0.40) | PIK3CD | |
| SCHEMBL13461316 | 0.82 | POLB (0.44) | KDM4EALDH1A1PIK3CDPOLBMEN1 | |
| SCHEMBL24267666 | 0.81 | MEN1 (0.40) | KDM4EALDH1A1ALOX15PIK3CDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020140054-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |
| WO-2020140052-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |