Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461316 | 0.98 | POLB (0.44) | POLBPIK3CDSIGMAR1TSHRGAA | |
| SCHEMBL23732159 | 0.96 | PIK3CD (0.42) | POLBPIK3CDSIGMAR1TSHRGAA | |
| SCHEMBL3421713 | 0.91 | PIK3CD (0.45) | POLBPIK3CDSIGMAR1TSHRGAA | |
| SCHEMBL23023701 | 0.86 | POLB (0.51) | POLBPIK3CDSIGMAR1 | |
| SCHEMBL13683385 | 0.86 | POLB (0.54) | POLBPIK3CDSIGMAR1TSHR | |
| SCHEMBL18021940 | 0.86 | POLB (0.51) | POLBPIK3CDSIGMAR1 | |
| SCHEMBL22175017 | 0.84 | KDM4E (0.42) | POLBPIK3CDSIGMAR1 | |
| SCHEMBL21107438 | 0.84 | POLB (0.46) | POLBPIK3CDSIGMAR1 | |
| SCHEMBL22861852 | 0.84 | POLB (0.46) | POLBPIK3CDSIGMAR1 | |
| SCHEMBL21105875 | 0.84 | POLB (0.46) | POLBPIK3CDSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | NUTECH VENTURES (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351883-B2 | Compounds for increasing lipid synthesis and storage | FASN, LIPC, SREBF2 | POLB 3520/4885PIK3CD 983/4885SIGMAR1 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.