Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22222383 | 0.92 | MIF (0.61) | MIFAPPP2RY6MAPTCA1 | |
| Phenylisothiocyanate SCHEMBL20984 | 0.81 | — | — | |
| SCHEMBL14996343 | 0.81 | APP (0.48) | MIFAPPP2RY6CA1CA2 | |
| SCHEMBL19057508 | 0.81 | P2RY6 (0.47) | MIFAPPP2RY6MAPTCA1 | |
| SCHEMBL14996360 | 0.81 | APP (0.48) | MIFAPPP2RY6CA1CA2 | |
| SCHEMBL23051721 | 0.81 | P2RY6 (0.47) | MIFP2RY6MAPTCA1CA2 | |
| SCHEMBL17225183 | 0.81 | P2RY6 (0.47) | MIFP2RY6MAPTCA1CA2 | |
| SCHEMBL1333233 | 0.79 | P2RY6 (0.45) | MIFP2RY6CA1CA2HSD17B10 | |
| Phenylisothiocyanate SCHEMBL2399995 | 0.79 | MIF (0.94) | MIFP2RY6MAPTCA1CA2 | |
| Phenylisothiocyanate SCHEMBL25197976 | 0.79 | MIF (0.94) | MIFP2RY6MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455563-B2 | Reactive mesogenic compounds and mixtures | MERCK PATENT GMBH (DE) | 2013-06-04 | — | — | US | claimed |
| EP-2227513-B1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | claimed |
| US-20110178200-A1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-07-21 | — | — | US | claimed |
| EP-2227513-A1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | Merck Patent GmbH (DE) | 2010-09-15 | — | — | EP | claimed |
| WO-2009086911-A1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | MERCK PATENT GMBH (DE) | 2009-07-16 | — | — | WO | claimed |
| CN-106978192-B | A kind of high birefringence rate liquid crystal compound and preparation method thereof with and combinations thereof | 西安近代化学研究所 | 2019-02-12 | — | — | CN | disclosed |
| US-8455563-B2 | Reactive mesogenic compounds and mixtures | MERCK PATENT GMBH (DE) | 2013-06-04 | — | — | US | disclosed |
| EP-2227513-B1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | disclosed |
| US-20110178200-A1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-07-21 | — | — | US | disclosed |
| EP-2227513-A1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | Merck Patent GmbH (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009086911-A1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | MERCK PATENT GMBH (DE) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178200-A1 | REACTIVE MESOGENIC COMPOUNDS AND MIXTURES | BLM, MITF, PARG | MIF 444/4885APP 1479/4885P2RY6 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.