SCHEMBL22178495

SCHEMBL22178495

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c5c6c7ccccc7n7c8ccccc8c(c8c9ccccc9n(c4c3)c85)c67)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 4/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 4/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
NTSR1 P30989 1/20 0.36
LMNA P02545 1/20 0.35
GLA P06280 1/20 0.35
ACP1 P24666 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA1 P30542 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601534 1.00 KMT2A (0.39) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL24601529 0.91 MEN1 (0.39) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL24601527 0.91 MEN1 (0.39) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL20200149 0.89 KMT2A (0.40) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL18820838 0.88 MEN1 (0.39) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL18820840 0.87 MEN1 (0.38) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL22178597 0.85 MAOB (0.41) ALDH1A1HPGDKDM4EHSD17B10
SCHEMBL24394912 0.84 KMT2A (0.36) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL20405047 0.84 MEN1 (0.36) KMT2AMEN1ALDH1A1HPGDMAPT
SCHEMBL24601656 0.84 KDM4E (0.35) KMT2AALDH1A1HPGDMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND OR10J3, ESR1, NFE2L2 KMT2A 1226/4885MEN1 1631/4885ALDH1A1 524/4885
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 KMT2A 2774/4885MEN1 1635/4885ALDH1A1 3824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.