Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2217876

N.NC(=O)CCC(=O)NO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.55
KDM4E B2RXH2 2/20 0.55
KDM5C P41229 2/20 0.55
PHF8 Q9UPP1 2/20 0.55
KDM2A Q9Y2K7 2/20 0.55
KDM6B O15054 1/20 0.55
EGLN1 Q9GZT9 1/20 0.55
HDAC2 Q92769 4/20 0.50
HDAC8 Q9BY41 4/20 0.50
HDAC6 Q9UBN7 4/20 0.50
HDAC1 Q13547 4/20 0.50
HDAC3 O15379 3/20 0.50
HDAC5 Q9UQL6 2/20 0.50
HSP90AA1 P07900 1/20 0.41
CA2 P00918 1/20 0.40
LMNA P02545 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
NFKB1 P19838 1/20 0.40
CA5A P35218 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137189 0.97
SCHEMBL27643837 0.97 FOLH1 (0.57) FOLH1KDM4EKDM5CPHF8KDM2A
SCHEMBL27971202 0.94 FOLH1 (0.55) FOLH1KDM4EKDM5CPHF8KDM2A
Hydrochloric Acid SCHEMBL28102677 0.94 FOLH1 (0.55) FOLH1KDM4EKDM5CPHF8KDM2A
Fluoride SCHEMBL27659982 0.94 FOLH1 (0.55) FOLH1KDM4EKDM5CPHF8KDM2A
Hydrogen Sulfide SCHEMBL27828695 0.94 FOLH1 (0.55) FOLH1KDM4EKDM5CPHF8KDM2A
Methyl Alcohol SCHEMBL28065375 0.92 HDAC2 (0.52) FOLH1KDM4EKDM5CPHF8KDM2A
Bicarbonate SCHEMBL28104388 0.92 FOLH1 (0.59) FOLH1KDM4EKDM5CPHF8KDM2A
Carbamic Acid SCHEMBL28072784 0.92 FOLH1 (0.59) FOLH1KDM4EKDM5CPHF8KDM2A
Nitrogen SCHEMBL28066207 0.92 FOLH1 (0.52) FOLH1KDM4EKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3202424-A1 KIT FOR FORMULATION OF LIPOSOMAL DOXORUBICIN MODIFIED WITH BIOACTIVE PEPTIDES FOR SELECTIVE TARGETING OF RECEPTORS OVEREXPRESSED BY CANCER CELLS Invectors S.r.l. (IT) 2017-08-09 EP disclosed
US-20170209474-A1 KIT FOR FORMULATION OF LIPOSOMAL DOXORUBICIN MODIFIED WITH BIOACTIVE PEPTIDES FOR SELECTIVE TARGETING OF RECEPTORS OVEREXPRESSED BY CANCER CELLS INVECTORS S.R.L. (IT) 2017-07-27 US disclosed
CN-106661074-A Synthesis of phosphoramidates 桑多斯股份公司 2017-05-10 CN disclosed
CN-106009079-A Coating rubber material for composite fiber modified printing rubber roll and preparation method of coating rubber material 铜陵宏正网络科技有限公司 2016-10-12 CN disclosed
CN-106009080-A Coating rubber material of fireproof printing rubber roller and preparation method of coating rubber material 铜陵宏正网络科技有限公司 2016-10-12 CN disclosed
CN-106009081-A Coating rubber material of lubricating printing rubber roller and preparation method of coating rubber material 铜陵宏正网络科技有限公司 2016-10-12 CN disclosed
CN-106009082-A Coating rubber material of environment-friendly printing rubber roll and preparation method of coating rubber material 铜陵宏正网络科技有限公司 2016-10-12 CN disclosed
CN-106009085-A Coating rubber material of printing rubber roller and preparation method of coating rubber material 铜陵宏正网络科技有限公司 2016-10-12 CN disclosed
CN-106009084-A Coating rubber material of ink-resistant printing rubber roll and preparation method of coating rubber material 铜陵宏正网络科技有限公司 2016-10-12 CN disclosed
CN-106009083-A Coating rubber material of aerogel printing rubber roll and preparation method of coating rubber material 铜陵宏正网络科技有限公司 2016-10-12 CN disclosed
CN-105968444-A Coating rubber material for toughened printing rubber rolls and preparation method of coating rubber material 铜陵宏正网络科技有限公司 2016-09-28 CN disclosed
US-20110177619-A1 IN VITRO DIAGNOSTIC MARKERS COMPRISING CARBON NANOPARTICLES AND KITS PITLAB LTD (GB) 2011-07-21 US disclosed
CN-101316619-A Natural biodegradable matrices and uses thereof SURMODICS INC (US) 2008-12-03 CN disclosed
CN-101309709-A Coatings and articles including natural biodegradable polysaccharides SURMODICS INC (US) 2008-11-19 CN disclosed
CN-101300036-A Coatings and articles including natural biodegradable polysaccharides SURMODICS INC (US) 2008-11-05 CN disclosed
CN-101001959-A Enzyme-based time temperature indicator CIBA SC HOLDING AG (CH) 2007-07-18 CN disclosed
CN-1318403-C Indoline derivatives substituted in the 6 position, their preparation and their use as medicaments BOEHRINGER INGELHEIM PHARMA (DE) 2007-05-30 CN disclosed
CN-1950114-A Natural biodegradable polysaccharide coatings for medical articles SURMODICS INC (US) 2007-04-18 CN disclosed
CN-1668589-A Indoline derivatives substituted in the 6-position, their preparation and their use as medicaments BOEHRINGER INGELHEIM PHARMA (DE) 2005-09-14 CN disclosed
CN-1319090-A Novel substuted indolimones, their preparation process and use as medicine BOEHRINGER INGELHEIM PHARMA (DE) 2001-10-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177619-A1 IN VITRO DIAGNOSTIC MARKERS COMPRISING CARBON NANOPARTICLES AND KITS CD63, LGALS3, MKI67 FOLH1 264/4885KDM4E 3356/4885KDM5C 2571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.