SCHEMBL22181202 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	NR1H2	P55055	1/20	0.51

▸	KDM4E	B2RXH2	1/20	0.41

▸	PKM	P14618	1/20	0.41

▸	GPR119	Q8TDV5	5/20	0.40

▸	HPGD	P15428	1/20	0.40

▸	MEN1	O00255	1/20	0.40

▸	ALDH1A1	P00352	1/20	0.40

▸	MAPT	P10636	1/20	0.40

▸	KMT2A	Q03164	1/20	0.40

▸	FAAH	O00519	1/20	0.40

▸	USP2	O75604	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	RECQL	P46063	1/20	0.39

▸	EPHX1	P07099	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29257891	0.90	NR1H2 (0.60)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL22181207	0.89	HPGD (0.47)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL31662254	0.85	HPGD (0.54)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL310405	0.85	HPGD (0.54)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL28526894	0.84	NR1H2 (0.47)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL364778	0.84	NR1H2 (0.51)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL6398279	0.84	NR1H2 (0.51)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL344474	0.84	NR1H2 (0.51)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL31662078	0.84	NR1H2 (0.51)	NR1H2KDM4EPKMGPR119HPGD
SCHEMBL22181462	0.83	NR1H2 (0.46)	NR1H2KDM4EPKMGPR119HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020138398-A1	NOVEL COMPOUND INHIBITING LYSINE-SPECIFIC DEMETHYLATING ENZYME 1, METHOD FOR PRODUCING SAME, AND USE OF SAME	国立研究開発法人理化学研究所	2020-07-02	—	—	WO	disclosed