Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.63 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.63 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.63 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | DRD1 | P21728 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | DRD4 | P21917 | 1/20 | 0.63 |
| ▸ | DRD5 | P21918 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | PTGFR | P43088 | 1/20 | 0.63 |
| ▸ | PTGIR | P43119 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099056 | 0.87 | PTGER3 (0.54) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL14880933 | 0.84 | HTR2C (0.51) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL22181196 | 0.84 | HTR2C (0.51) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL1208094 | 0.84 | HTR2C (0.55) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL31562813 | 0.83 | PTGER4 (0.53) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL22181470 | 0.78 | HTR2C (0.68) | DRD2HTR2CHTR2BHTR1ASLC6A2 | |
| SCHEMBL1208921 | 0.78 | HTR2A (0.50) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL17103923 | 0.78 | HTR2A (0.50) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL30483943 | 0.77 | ALDH1A1 (0.55) | PTGER1PTGER4PTGER3PTGER2DRD2 | |
| SCHEMBL18923955 | 0.77 | CYP4F2 (0.58) | SLC6A2SLC6A3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138398-A1 | NOVEL COMPOUND INHIBITING LYSINE-SPECIFIC DEMETHYLATING ENZYME 1, METHOD FOR PRODUCING SAME, AND USE OF SAME | 国立研究開発法人理化学研究所 | 2020-07-02 | — | — | WO | disclosed |