Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.49 |
| ▸ | HEXA | P06865 | 7/20 | 0.47 |
| ▸ | HEXB | P07686 | 7/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181861 | 0.89 | SIRT1 (0.53) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22181902 | 0.87 | SIRT1 (0.57) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22181894 | 0.85 | SIRT1 (0.53) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22181988 | 0.85 | SIRT1 (0.53) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22181854 | 0.85 | SIRT1 (0.57) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22182117 | 0.84 | SIRT1 (0.50) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22181892 | 0.83 | SIRT1 (0.51) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22181859 | 0.82 | HEXA (0.63) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22181986 | 0.82 | SIRT1 (0.47) | SIRT1HEXAHEXBOGAHDAC3 | |
| SCHEMBL22182084 | 0.82 | SIRT1 (0.47) | SIRT1HEXAHEXBOGAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020139291-A1 | NAPHTHALIMIDE DERIVATIVES AS ANTI-PARASITIC AGENTS FOR THE TREATMENT OF LEISHMANIASIS AS WELL AS VIRAL, BACTERIAL AND NEOPLASTIC DISEASES | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2020-07-02 | — | — | WO | disclosed |