Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 7/20 | 0.53 |
| ▸ | HEXB | P07686 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181868 | 0.81 | HEXA (0.67) | HEXAHEXBDRD2DRD3HTR1A | |
| SCHEMBL22182013 | 0.73 | HEXA (0.62) | HEXAHEXBDRD2DRD3HTR1A | |
| SCHEMBL22181867 | 0.68 | HEXA (0.47) | HEXAHEXBDRD2DRD3HTR1A | |
| SCHEMBL22181920 | 0.67 | SIRT1 (0.61) | HEXAHEXBSIRT1MEN1KMT2A | |
| SCHEMBL22181909 | 0.67 | SIRT1 (0.57) | HEXAHEXBSIRT1MEN1KMT2A | |
| SCHEMBL22181918 | 0.66 | SIRT1 (0.60) | HEXAHEXBSIRT1MEN1KMT2A | |
| SCHEMBL13909959 | 0.66 | SIRT1 (0.75) | HEXAHEXBSIRT1MEN1KMT2A | |
| SCHEMBL22181988 | 0.66 | SIRT1 (0.53) | HEXAHEXBSIRT1MEN1KMT2A | |
| Bnipdeta SCHEMBL13909965 | 0.65 | SIRT1 (0.88) | HEXAHEXBSIRT1MEN1KMT2A | |
| Bnipdpta SCHEMBL13909966 | 0.65 | SIRT1 (0.88) | HEXAHEXBSIRT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020139291-A1 | NAPHTHALIMIDE DERIVATIVES AS ANTI-PARASITIC AGENTS FOR THE TREATMENT OF LEISHMANIASIS AS WELL AS VIRAL, BACTERIAL AND NEOPLASTIC DISEASES | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2020-07-02 | — | — | WO | disclosed |