Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.43 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792766 | 0.87 | PDGFRB (0.40) | SMN1; SMN2PDGFRBKDRLMNA | |
| SCHEMBL22792755 | 0.84 | LPL (0.43) | LPLLIPGCNR1PDGFRBKDR | |
| SCHEMBL22182243 | 0.83 | LPL (0.42) | LPLLIPGIDO1CA1CA2 | |
| SCHEMBL22182206 | 0.81 | FGFR1 (0.42) | FGFR1LPLLIPGIDO1CA1 | |
| SCHEMBL16655918 | 0.80 | LPL (0.41) | LPLLIPGGAAPDGFRBKDR | |
| SCHEMBL16342432 | 0.79 | FGFR1 (0.65) | FGFR1KDR | |
| SCHEMBL22182214 | 0.79 | LPL (0.40) | LPLLIPGIDO1CXCR2 | |
| SCHEMBL22182428 | 0.78 | FGFR1 (0.44) | FGFR1LPLLIPGKDRIDO1 | |
| SCHEMBL22792514 | 0.77 | LPL (0.48) | LPLLIPGALDH1A1PDGFRBKDR | |
| SCHEMBL22182173 | 0.75 | FGFR1 (0.48) | FGFR1SMN1; SMN2GAACNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020135878-A1 | IMIDAZOPYRIDINE DERIVATIVE AS FGFR AND VEGFR DUAL INHIBITOR | 南京明德新药研发有限公司 | 2020-07-02 | — | — | WO | disclosed |