Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19760321 | 0.89 | GPR3 (0.41) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL22930686 | 0.86 | MAPT (0.38) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL15434193 | 0.85 | MAPT (0.35) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL22930695 | 0.85 | MEN1 (0.35) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL18732175 | 0.82 | PDK2 (0.37) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL24557138 | 0.80 | MAPT (0.38) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL19299502 | 0.80 | MEN1 (0.38) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL20371275 | 0.79 | MIF (0.36) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL22930694 | 0.79 | MAPT (0.39) | MAPTMEN1POLBKMT2ADUSP3 | |
| SCHEMBL20224560 | 0.78 | PDK2 (0.38) | MAPTMEN1POLBKMT2ADUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419960-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-01 | — | — | EP | disclosed |