SCHEMBL22187022

SCHEMBL22187022

C=C(C)C(=O)OC(C)NC(C)(C)C.C=C(C)C(=O)OC(O)CC

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26305 0.87 ALDH1A1 (0.43) TSHRALDH1A1
Fluoride SCHEMBL8582112 0.85 ALDH1A1 (0.41) TSHRALDH1A1
1,1-Dichloroethene SCHEMBL10925549 0.82 ALDH1A1 (0.39) TSHRALDH1A1
Methacrylic Acid SCHEMBL21611350 0.82 ALDH1A1 (0.39) TSHRALDH1A1
SCHEMBL27862593 0.82 ALDH1A1 (0.54) TSHRALDH1A1
SCHEMBL25040 0.82 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL1072340 0.81 TSHR (0.33) TSHRALDH1A1
SCHEMBL21899773 0.81 TSHR (0.49) TSHRALDH1A1THRB
Methane SCHEMBL7698380 0.80 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL28381594 0.80 TSHR (0.42) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111053775-B Physiologically cool active ingredient and use of substances containing such active ingredient 西姆莱斯股份公司 2023-08-18 CN disclosed
EP-3675809-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS BASF SE (DE) 2020-07-08 EP disclosed