Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CAMK1D | Q8IU85 | 4/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | BLK | P51451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28605693 | 0.99 | IDH2 (0.51) | IDH2HRH4LMNALCKKDR | |
| Hydrochloric Acid SCHEMBL28605691 | 0.99 | IDH2 (0.51) | IDH2HRH4LMNALCKKDR | |
| SCHEMBL22186838 | 0.92 | IDH2 (0.43) | IDH2HRH4LMNALCKKDR | |
| Hydrochloric Acid SCHEMBL28919352 | 0.90 | IDH2 (0.43) | IDH2HRH4LMNALCKKDR | |
| Hydrochloric Acid SCHEMBL28919350 | 0.90 | IDH2 (0.43) | IDH2HRH4LMNALCKKDR | |
| SCHEMBL22186377 | 0.86 | IDH2 (0.52) | IDH2HRH4LMNALCKKDR | |
| SCHEMBL13315593 | 0.86 | KDM4E (0.56) | IDH2HRH4LMNALCKKDR | |
| SCHEMBL22186372 | 0.80 | PIM1 (0.47) | IDH2PIM1PIM2PBKAKT1 | |
| Hydrochloric Acid SCHEMBL28596259 | 0.79 | PIM1 (0.46) | IDH2KDM4EPIM1PIM2PBK | |
| Hydrochloric Acid SCHEMBL28596260 | 0.79 | PIM1 (0.46) | IDH2KDM4EPIM1PIM2PBK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138271-A1 | HETEROCYCLIC DERIVATIVES AS Nav1.7 and Nav1.8 BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2020-07-02 | — | — | WO | disclosed |