Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28596260 | 0.99 | PIM1 (0.46) | PIM1PIM2FFAR4DRD3IDH2 | |
| Hydrochloric Acid SCHEMBL28596259 | 0.99 | PIM1 (0.46) | PIM1PIM2FFAR4DRD3IDH2 | |
| SCHEMBL28605632 | 0.80 | FFAR4 (0.44) | FFAR4DRD3NOTUM | |
| SCHEMBL28605634 | 0.80 | FFAR4 (0.44) | FFAR4DRD3NOTUM | |
| SCHEMBL22187069 | 0.80 | IDH2 (0.52) | PIM1PIM2IDH2PBKAKT1 | |
| SCHEMBL22816476 | 0.80 | PIM1 (0.46) | PIM1PIM2FFAR4KDM1ANOTUM | |
| Hydrochloric Acid SCHEMBL28605691 | 0.79 | IDH2 (0.51) | PIM1PIM2IDH2PBKAKT1 | |
| Hydrochloric Acid SCHEMBL28605693 | 0.79 | IDH2 (0.51) | PIM1PIM2IDH2PBKAKT1 | |
| SCHEMBL31318672 | 0.74 | ALDH1A1 (0.43) | FFAR4DRD3KDM1ANOTUM | |
| SCHEMBL29699554 | 0.74 | FFAR4 (0.56) | FFAR4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138271-A1 | HETEROCYCLIC DERIVATIVES AS Nav1.7 and Nav1.8 BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2020-07-02 | — | — | WO | disclosed |