Cyanate

Cyanate

SCHEMBL22187751

Cc1cccc(N=C=O)c1N=C=O.N#CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.53
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
TRPA1 O75762 1/20 0.40
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HSP90AA1 P07900 1/20 0.34
ATM Q13315 1/20 0.34
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 2/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30520271 0.91 CYP3A4 (0.63) CYP3A4GABRA1GABRB2TRPA1MEN1
SCHEMBL20145 0.91 CYP3A4 (0.63) CYP3A4GABRA1GABRB2TRPA1MEN1
Methane SCHEMBL10941733 0.89 CYP3A4 (0.61) CYP3A4GABRA1GABRB2TRPA1MEN1
Alcohol SCHEMBL9810773 0.86 CYP3A4 (0.53) CYP3A4GABRA1GABRB2TRPA1MEN1
Urea SCHEMBL17063541 0.86 CYP3A4 (0.53) CYP3A4GABRA1GABRB2TRPA1MEN1
SCHEMBL1669008 0.86 CYP3A4 (0.57) CYP3A4GABRA1GABRB2TRPA1MEN1
SCHEMBL28953537 0.86 CYP3A4 (0.57) CYP3A4GABRA1GABRB2TRPA1MEN1
SCHEMBL11667361 0.84 CYP3A4 (0.59) CYP3A4GABRA1GABRB2TRPA1MEN1
Toluene SCHEMBL27882185 0.83 CYP3A4 (0.53) CYP3A4GABRA1GABRB2TRPA1MEN1
SCHEMBL374209 0.79 GABRA1 (0.56) CYP3A4GABRA1GABRB2TRPA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3675675-A1 METHOD FOR WELDING POROUS MEMBRANES BASF SE (DE) 2020-07-08 EP disclosed